Actionable NTM Answers
in 2 to 3 Days

Q: What organisms are covered?

NTM-Seq identifies 170+ NTM species, including M. avium complex, M. abscessus (resolved to subspecies), M. kansasii and M. xenopi.

Species-level identification and resistance markers, direct from respiratory samples or from positive cultures and isolates.

The Challenge

NTM Pulmonary Disease Is Rising. Current Diagnostics Haven't Kept Up.

The incidence of NTM pulmonary disease is increasing worldwide, yet diagnosis remains slow and imprecise. Traditional culture-based methods can take weeks to return results, and conventional identification often fails to distinguish between species, a critical gap when treatment regimens differ significantly between organisms like M. abscessus and M. avium complex.

Weeks to Wait

Culture-based NTM identification is slow, delaying diagnosis and treatment

Rising Incidence

NTM pulmonary disease is increasing worldwide, especially in developed nations

Critical Gap

Species-level ID is essential: treatment differs significantly between organisms

What You Get

NTM-Seq Results. One Test.

170+ NTM Species Detection

Broad coverage across the full spectrum of clinically relevant NTM species

Genotypic Resistance Characterization

Genomic markers for antimicrobial resistance to guide treatment selection

No Organism Growth Needed

Direct-from-sample testing eliminates the wait for culture

Tests

Wherever the specimen is in your workflow.

Send it at whatever stage you have it. Results in 2 to 3 days.

NTM-Seq Direct

3 days

Sputum or BAL

Targeted hybrid capture, direct from the specimen. No culture step. 170+ NTM species, M. abscessus to subspecies, and macrolide resistance markers including erm(41) sequevar. rrl and rrs launching Q4 2026.

NTM-Seq Culture

2 days

Positive liquid culture bottles and pure culture isolates

Whole-genome sequencing. Species, subspecies, and macrolide resistance markers including erm(41) sequevar. rrl and rrs launching Q4 2026. From a positive bottle: species, subspecies and resistance genotype in 2 days, without waiting for subculture or a reference lab ID.

Clinical Benefits

Better Information. Better Decisions.

Earlier Organism ID

Species-level identification in days instead of weeks

Earlier Resistance Insight

Genotypic resistance data before phenotypic testing is possible

Reduced Diagnostic Uncertainty

Detection across 170+ species, including rare and slow-growing NTM

Improved Treatment Confidence

Actionable data to support informed clinical decisions

The Technology

NTM-Seq: Powered by
Next-Generation Sequencing

NTM-Seq Direct uses targeted hybrid capture on sputum or BAL. NTM-Seq Culture uses whole-genome sequencing on positive culture bottles and isolates.

Broad Species Coverage

Our curated database covers 170+ NTM species, including rare and emerging organisms.

Next-Generation Sequencing

Targeted NGS extracts and sequences DNA directly from respiratory samples, bypassing the slow culture step entirely.

Genomic Analysis

Bioinformatics pipelines scan for resistance-associated mutations and genes, providing genotypic insight alongside species ID.

Clear Reporting

Results are delivered in a clinician-friendly format with species identification, resistance markers, and clinical context.

How It Works

From Sample to Actionable Report

Sample Collection

Respiratory sample is collected and submitted using standard clinical workflows.

Direct Sequencing

DNA is extracted and sequenced directly from the sample: no culture step, no waiting weeks.

Bioinformatics

Advanced computational analysis identifies NTM species and resistance markers from sequencing data.

Clinical Report

A clear, comprehensive report is delivered with species identification and treatment-relevant insights.

Who It's For

Built for the Clinicians and Labs
Fighting NTM Disease

Pulmonologists

Get species-level NTM identification to guide treatment decisions for patients with NTM pulmonary disease, bronchiectasis, and chronic lung infections.

Infectious Disease Specialists

Species-level NTM identification and genotypic resistance markers to inform targeted antibiotic regimens.

Clinical Microbiology Labs

NGS-based NTM identification across 170+ species, with resistance markers in the same report.

FAQ

Frequently Asked Questions

NTM-Seq Direct accepts sputum and bronchoalveolar lavage (BAL). NTM-Seq Culture accepts positive liquid culture bottles and pure culture isolates.

NTM-Seq identifies 170+ NTM species, including M. avium complex, M. abscessus (resolved to subspecies), M. kansasii and M. xenopi.

NTM-Seq Direct results are delivered in 3 days. NTM-Seq Culture results, from positive bottles and isolates, are delivered in 2 days. Culture-based identification can take weeks.

All patient data is handled in compliance with HIPAA requirements.

Contact us to set up an account and receive a sample collection kit with detailed instructions. Samples are shipped to our CLIA-certified laboratory by courier.

NTM-Seq Direct does not. It sequences directly from the clinical sample, with no culture step. NTM-Seq Culture runs on a positive bottle or isolate.

Interested in NTM-Seq?

We're working with clinicians and laboratories who are ready to move beyond the limitations of conventional NTM diagnostics. Get in touch to learn more.

Actionable NTM Answers in 2 to 3 Days